The life of Queen Insoo from her childhood to adulthood as she ruled Joseon alongside her mother-in-law, Queen Jeonghee. The drama spans from King Moon Jong to Yeon San, Insoo's grandson.

A community is driven into a state of tension and paranoia as more and more children mysteriously go missing. In the midst of this, Ji Soo and Hyun Soo's daughter, Soo Ah, is also kidnapped. A special kidnapping rescue squad is dispatched to investigate the case, attempting to find out where the children disappeared to and whether or not they're still alive.