Seo Eun Young and Kang Jung Woo are happy, engaged-to-be-married couple. Suddenly, when Eun Young was pregnant, Jung Woo abandoned her to marry Na Kyung, a rich woman. The new couple then went to study abroad for 5 years. Meanwhile, Eun Young works as a nurse in a hospital. Kang Hyung Woo, who is one of her patients, becomes obsessed with her. Hyung Woo’s mother, Madam Shin, a department store owner, then wants Eun Young to marry her son.

Choi Gi Chan is an University Botanic Professor with the "perfect genes." The drama is about an editor of a fashion magazine, Kim Dang Ja, who suddenly develops an urge to have her own baby despite opposing the idea of marriage. The story will talk about Dang Ja striving to look for a man with perfect genes to accomplish her mission. Gi Chan happens to be her "target" in order for her to accomplish her mission. The story later develops as Dang Ja must persuade him to do it without any commitments, which is a problem because Gi Chan doesn't believe in the idea of sex before marriage.