When Homicide Detective Kang Oh Soo hit a dead end in his investigation of two seemly unrelated murders, except for the Tarot cards left behind at both crime scenes, he sought help from Seo Hae In, a woman with psychometry ability. She revealed that the killers were different in each murder, but the victims were chosen for their connection to a death of a high school boy. Later, the cases proved to have one more thing in common: the suspects have the same defense attorney, Oh Seung Ha.
Seung Ha's defense for his clients severely shaken Oh Soo’s conviction to catch the Tarot Card mastermind. Oh Soo was reminded that years ago he had killed a high school classmate in a fight. He was acquitted of all charges and began his life anew. Now, someone has came back to revenge the boy’s wrongful death by killing those who got him off.
Yoon Seok Joo is a producer who abandons his common law wife, Seo Young, to attain success. They have a daughter together but he later betrays Seo Young when he marries a rich man's daughter, Lee Jung Min. Lee Sang Min is an owner of a film company and is a new film director. He is also Jung Min's half brother. Sang Min will be a rival to Seok Joo in work and in love for Seo Young. Yoon Hyun Joo lost her dad at a young age and went through serious hardships and became a successful architect and is Seok Joo's sister. This drama is also about the lives of five siblings.
As the director of her father's advertising company, Ma Yoo Hee (Han Ga In) is known as a witch for her ruthless, no nonsense character. After a string of failed attempts to hire a housekeeper, she (literally) runs into Chae Moo Ryong (Jae Hee), ex-medical student turned aspiring chef. As a way to work off his debt for crashing into her car, he agrees to become her housekeeper and personal love affairs coach for one month. Gladly, he gives her a makeover that attracts both her old friend Johnny Kruger (Dennis Oh) and her first love Joon Ha (Kim Jeong Hoon). Despite having a girlfriend, Sung Mi (Jun Hye Bin), Moo Ryong eventually finds himself falling for Yoo Hee.
Suh Jin Young is an aviation maintenance technician. Her fiance Jae Hoon passed away in a horrible traffic accident. Kim Chae Joon dreams of becoming an aviation maintenance technician but he encounters prejudice because he is an ex-convict. He killed some one with his car. Suh Jin Young gives him a chance to work under her and they fall in love. However that love is severely tested when they both discover that the Chae Joon's victim was Suh Jin Young's fiance Jae Hoon.
Lee Ji Yeon has a natural, affirmative and bright personality and is an accessory designer. Kim Tae Seop is a dectective who is very quiet and is devoted to Ji Yeon after he falls in love with her. Ji Yeon is caught between two men.
Oh Dal Ja is 33 years old and she is an MD of a home shopping channel. She has a "love contract" with Kang Tae Bong, a 27 year old freelancer of a playmate enterprise. The story also revolves around Dal Ja's life with three men. Wee Sun Joo is a divorcee who is an expert on love and faces life with positive thinking.
Based on the popular Internet novel, "Multi-Cell Girl", the film takes place in "No-Use High School", a school renowned for its sexual aberrations. The student body is comprised of sexually ambiguous teenagers, and the student president and vice-present flaunt their taste for S&M. Independent study and supplementary classes are done on homosexuality and transgenderism, and teachers and students alike leave school early because of sexually-transmitted diseases. But amidst this environment, there are some that just can't adapt. Among them: "Poor Girl", a student who earns money for her family by sleeping with older men; "Anthony", a luxurious pretty-boy from Switzerland; and "One-Eye", the school's sole virgin. Poor Girl falls in love with Anthony at first sight. Meanwhile, Anthony is struck by One-Eye's brother "Two Eyes" and feels confused about his sexuality.